Problem 9 Describe the events that occur a... [FREE SOLUTION] (2024)

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Chapter 26: Problem 9

Describe the events that occur at a synapse when a neural impulse arrives at asynaptic terminal of a presynaptic cell.

Short Answer

Expert verified

Neural impulse causes Ca²⁺ influx, triggering neurotransmitter release, which binds to postsynaptic receptors, generating a synaptic response.

Step by step solution

01

- Arrival of the Neural Impulse

When a neural impulse (action potential) arrives at the synaptic terminal of the presynaptic cell, it causes the depolarization of the presynaptic membrane.

02

- Opening of Voltage-Gated Calcium Channels

The depolarization opens voltage-gated calcium (Ca²⁺) channels in the presynaptic membrane, allowing Ca²⁺ ions to enter the synaptic terminal.

03

- Neurotransmitter Release

The influx of Ca²⁺ ions causes synaptic vesicles filled with neurotransmitters to merge with the presynaptic membrane and release their contents into the synaptic cleft.

04

- Binding to Receptors

Neurotransmitters diffuse across the synaptic cleft and bind to specific receptors on the postsynaptic membrane.

05

- Postsynaptic Response

The binding of neurotransmitters to receptors on the postsynaptic cell can result in either excitatory postsynaptic potentials (EPSPs) or inhibitory postsynaptic potentials (IPSPs), depending on the type of neurotransmitter and receptor involved.

06

- Termination of Signal

The signal is terminated when neurotransmitters are either reabsorbed by the presynaptic cell, degraded by enzymes, or diffuse away from the synaptic cleft.

Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Neural Impulse

A neural impulse, also known as an action potential, is the way nerve cells communicate. It is a brief electrical charge that travels down the axon of a neuron. This process begins when the neuron receives a sufficient stimulus, causing a change in electrical charge across its membrane.
Neurons maintain a resting membrane potential due to differences in ion concentrations inside and outside the cell. When an action potential happens, there is a rapid depolarization of the membrane.
The change in electrical charge along the neuron helps transmit signals quickly along the nervous system. When this impulse reaches the end of the neuron, it causes various events in the synaptic terminal, leading to neurotransmitter release.

Synaptic Terminal

The synaptic terminal is the endpoint of a neuron where the communication with another cell occurs. It's packed with synaptic vesicles, which are tiny sacs containing neurotransmitters—the chemicals responsible for transmitting signals across the synapse.
When a neural impulse reaches the synaptic terminal, it plays a crucial role in converting the electrical signal into a chemical signal. This conversion is essential for the communication between neurons and between neurons and other types of cells.
The presynaptic membrane of the synaptic terminal is responsible for the release of neurotransmitters into the synaptic cleft, a small gap separating the presynaptic neuron from the postsynaptic cell.

Neurotransmitter Release

Neurotransmitter release is a key event that occurs after a neural impulse arrives at the synaptic terminal. The arrival of the action potential causes depolarization of the presynaptic membrane, leading to the opening of voltage-gated calcium channels.
Calcium ions (Ca²⁺) flow into the presynaptic cell, which is the driving force behind the synaptic vesicles merging with the membrane. This process, known as vesicle fusion, releases neurotransmitters into the synaptic cleft.
Released neurotransmitters then diffuse across the synaptic cleft and bind to receptors on the membrane of the postsynaptic cell, triggering further cellular responses.

Calcium Channels

Calcium channels are vital proteins located in the membrane of the presynaptic terminal. They are sensitive to changes in voltage and are specifically designed to allow Ca²⁺ ions to pass through.
When an action potential reaches the synaptic terminal, it causes the depolarization of the presynaptic membrane, prompting these voltage-gated calcium channels to open.
This opening allows calcium ions to rush into the synaptic terminal's interior. The influx of calcium ions is critical because it signals synaptic vesicles to merge with the presynaptic membrane and release neurotransmitters.

  • This release is the magic behind synaptic communication.

  • Calcium channels thus act as gatekeepers, controlling the entry of calcium ions and thus the release of neurotransmitters.

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Problem 9 Describe the events that occur a... [FREE SOLUTION] (3)

Most popular questions from this chapter

Neuroglia outnumber neurons in the nervous system by about 10 to 1 Inaddition, neuroglia retain the ability to divide, unlike most neurons. How dothese two observations relate to the fact that most brain cancers begin inglial cells?Prescription sleep aids, like Ambien, bind to inhibitory receptors on neurons.Explain how these drugs slow the production of action potentials in affectedparts of the brain.What is the connection between the threshold potential and an actionpotential? What happens to sodium and potassium ions as the membrane isdepolarized and repolarized? How does the membrane restore its restingpotential?How do the nervous and endocrine systems differ in how they communicate?Use the following activity to visualize the ion movements of an actionpotential: If you're in a classroom with several other students, label half ofthem as sodium ions and half as potassium ions. Find an object to represent amembrane (e.g., a line in the floor); label four mats or pieces of paper torepresent different membrane proteins, and lay them across the line. Choosewhich side will be the inside of the cell. Act out how the ions move before,during, and after an action potential. Alternatively, if you are working aloneor in a small group, use 20 coins of two different types to represent \(10\mathrm{Na}^{+}\) and \(10 \mathrm{K}^{+}\) ions. Draw a line on a piece of paperto serve as a membrane, add four types of proteins, and label the inside andoutside of the cell. Position the ions before, during, and after an actionpotential. Then, write a sentence or two about your activity.
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Problem 9 Describe the events that occur a... [FREE SOLUTION] (2024)

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